JACC This Week
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JACC This Week
Weekly summary and focused insights of the high-impact cardiovascular research published in the JACC from Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC, shaping cardiovascular care today.
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December 2, 2025: Global CVD 1990–2023: Trends, Risks, and the Road Ahead | JACC This Week
In the December 2, 2025 episode of JACC This Week, Editor-in-Chief Harlan M. Krumholz, MD, SM, introduces the Spotlight Issue, anchored by the manuscr...
November 25, 2025: Clonal Hematopoiesis, Alcohol and Blood Pressure, Long-Term Risk, and Emerging Biomarkers | JACC This Week
JACC's November 25, 2025 issue kicks off Thanksgiving week with JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, reflecting on his editor's page and t...
November 18, 2025: Adiposity, Heart Failure, and the Future of Cardiometabolic Care | JACC This Week
In the November 18, 2025 issue of JACC, Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC, uses his editor's page to reflect on the evolving role of ed...
November 11, 2025: Precision, Place, and the Future of Cardiovascular Prediction | JACC This Week
In this week's JACC podcast, Editor-in-Chief Dr. Harlan Krumholz explores how context, precision, and physiology converge to shape modern cardiovascul...
November 4, 2025: The 2025 Hypertension Guideline: A New Era in Blood Pressure Control | JACC This Week
In this special episode of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz introduces the November 4, 2025 issue, entirely devoted to hypertension...
October 28.2025: How Low Should We Go? | JACC This Week
Dr. Harlan Krumholz introduces a JACC issue unified around the question of how low to target blood pressure, highlighting growing evidence that aiming...
October 21, 2025 - The Adipokine Hypothesis, Adipose-Cardiac Signaling, Sex Differences, Therapeutic Implications, and Diverse Populations | JACC This Week
JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, introduces the October 21, 2025 issue of JACC, which is devoted entirely to Dr. Milton Packer's adipo...
October 14, 2025 - Emerging Frontiers in Cardiovascular Medicine: From Certification Reform to Inflammation Targeting | JACC This Week
This episode of JACC This Week, hosted by Harlan M. Krumholz, MD, SM, highlights key research and perspectives from the October 14, 2025 issue of JACC...
October 7, 2025: AI in Scientific Writing and New Frontiers in Cardiovascular Care | JACC This Week
In the October 7, 2025 issue of JACC, Editor-in-Chief Harlan Krumholz discusses how artificial intelligence can enhance clarity in scientific writing—...
Computable Quality, Community Screening, and TAVR Debate | JACC This Week
In the September 30 issue of JACC, Editor-in-Chief Dr. Harlan Krumholz explores the concept of "computable quality" in healthcare, advocating for real...
AI, Polygenic Risk Scores, and Antithrombotic Therapy | JACC This Week
In this episode, Editor-in-Chief Harlan Krumholz explores the evolving landscape of cardiovascular medicine, beginning with a call for responsible ste...
Reframing Cardiovascular Care | JACC This Week
In this episode, Dr. Harlan Krumholz introduces the September 16, 2025 issue of JACC, which features studies that challenge conventional clinical thin...
Heart Failure Insights, AI Standards, and Genetic Clues | JACC This Week
In this episode, Dr. Harlan Krumholz reviews the September 9, 2025 issue of JACC, covering key studies on artificial intelligence in cardiovascular re...
Cognitive Risk in CHD and Cardiology Practice Meets Lifestyle Realities | JACC This Week
In the September 2, 2025 JACC This Week, Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC highlights the issue. Listen here for a summary of our lates...
Pacing Strategies, Air Quality, and the Path to Equity | JACC This Week
In this week's issue, Dr. Harlan Krumholz highlights new science with direct clinical implications: a randomized trial showing conduction system pacin...
Device Safety, DAPT Strategy & Structural Innovation | JACC This Week
In this episode of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz explores device safety, abbreviated DAPT, drug-coated balloons, and a novel su...
Amyloidosis in Focus: Biomarkers, Structural Insights & Therapeutic Strategy | JACC This Week
In this mini focus issue of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz explores the evolving landscape of cardiac amyloidosis care. From stru...
Out-of-Hospital Cardiac Arrest in Septuagenarians, Octogenarians, and Nonagenarians in Japan: Trends and Patterns in Outcomes | JACC Baran
Hosts Mitsuaki Sawano, MD, Shun Kohsaka, MD, and Nobuhiro Ikemura, MD, welcome Yuichi Saito, MD, of Chiba University Hospital, to discuss recent trend...
Zeroing In on Prevention: ARIC and the Future of Cardiovascular Risk | JACC Baran
Hosts Mitsuaki Sawano, MD, Shun Kohsaka, MD, Kentaro Ejiri, MD, and Satoshi Shoji, MD, welcome Dr. Kunihiro Matsushita of Johns Hopkins University to...
Epidemiology and Outcomes in HFimpEF | JACC Deep Dive
In this JACC Deep Dive, Editor-in-Chief Harlan M. Krumholz, MD, SM, discusses a large real-world study by Min et al. examining heart failure with impr...
Heart Failure in Practice: Dual Therapy Insights, Digital Innovation & the Future of Risk Models | JACC This Week
In this focus issue on Heart Failure in Practice, JACC Editor-in-Chief Dr. Harlan Krumholz examines how contemporary research continues to refine and...
JACC Editor's Page: June 30, 2025 | JACC
Cardiac electrophysiology is rapidly evolving, blending procedural expertise with innovations in pharmacotherapy, device design, and lifestyle medicin...
JACC Editor's Page: July 7. 2025 | JACC
Interventional cardiology is rapidly evolving, with advances in imaging, devices, and techniques driving both innovation and rising expectations for s...
IHCA Incidence Rates | JACC Deep Dive
In this JACC Deep Dive, Harlan M. Krumholz, MD, SM, FACC, discusses a new study in the July 8 issue of JACC, authored by Saket Girotra MD, SM, et al....
Plaque Vulnerability and Risk Factors | JACC Deep Dive
In this JACC Deep Dive, Harlan M. Krumholz, MD, SM, FACC reviews a study by Covani, et al that uses OCT imaging in over 1,500 ACS patients to show how...
Validation of AHA PREVENT in Healthcare Populations | JACC Deep Dive
Validation of AHA PREVENT in healthcare populations| JACC Deep Dive In this JACC Deep Dive, JACC Editor in Chief Harlan M. Krumholz, MD, SM, explores...
ACURATE neo2 Under-Expansion | JACC Deep Dive
JACC's July 29 issue explores why the ACURATE neo2 valve failed in its IDE trial, with a post-hoc analysis pointing to under-expansion in heavily calc...
Structural Heart Disease, Obesity-Related Heart Failure, Private Equity Ownership in Hospitals | JACC This Week
In this episode of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz introduces the journal's new design and highlights key studies from the July 29...
Prevention in Focus: Polypill Projections, Risk Equations & Global Syndemic Trends | JACC This Week
In this special prevention-focused issue of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz spotlights new research that underscores the urgent gl...
Cardiovascular Interventions in Focus: Plaque Vulnerability, PCI Outcomes & Outpatient Cardiac Care Trends | JACC This Week
In this episode of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz summarizes key studies from the July 15 issue, focused on cardiovascular interv...
Electrophysiology in Focus: AFIB Management, LAA Closure Insights and Stroke Risk Strategies | JACC This Week
In this episode of JACC This Week, Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC spotlights major electrophysiology research and clinical insights...
Podcasts at JACC: Past and Future | JACC This Week
As the podcast series created by Editor Emeritus Valentin Fuster, MD, PhD, MACC, comes to an end and the new series from current Editor-in-Chief Harla...
JACC Editor's Page: June 23, 2025 | JACC
In this heartfelt reflection on their first year as editor of JACC, Harlan Krumholz shares how listening—to authors, reviewers, readers, and the broad...
Wildfire-Linked Heart Failure, Impella Trial Insights, Cognitive Impairment in CVD & New Mortality Data | JACC This Week
In this debut episode of JACC This Week with Editor-in-Chief Dr. Harlan Krumholz, we explore groundbreaking studies and timely insights from the July...
JACC Editor's Page: June 16, 2025
In this issue of JACC, we explore the evolving landscape of cardiovascular care, where one-size-fits-all approaches are giving way to precision strate...
Long-term Survival and Patient Reported Outcomes after Staged Reconstructive Surgery for Hypoplastic Left Heart Syndrome | JACC
In this episode, Dr. Valentin Fuster presents new research revealing that fewer than one-third of patients with hypoplastic left heart syndrome surviv...
Relationship between exercise-induced cardiac troponin elevations and occult coronary atherosclerosis in middle-aged athletes | JACC
In this episode, Dr. Valentin Fuster discusses a study showing that elevated cardiac troponin levels after intense exercise in middle-aged recreationa...
Differences in Arterial Events in Ehlers-Danlos, Loeys-Dietz, and Marfan Syndrome | JACC
In this episode, Dr. Valentin Fuster discusses a landmark study from the Montalcino Aortic Consortium revealing how genetic differences in Marfan synd...
Characterization of Arterial Aneurysms in Loeys-Dietz Syndrome | JACC
In this episode, Dr. Valentin Fuster discusses a major study on Loeys-Dietz syndrome (LDS), revealing that extra-aortic arterial aneurysms are both co...
June 24, 2025 Issue Summary | JACC
In this JACC podcast, Dr. Valentin Fuster presents five key studies, including new insights into arterial aneurysms in genetic aortopathies like Loeys...